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Adding resistance training and adequate protein intake can further improve this ratio in favor of fat loss

Despite the lack of extra support for lifestyle modification as part of the SURPASS program, 4069% of patients achieved 10% weight loss with the highest doses of tirzepatide (1015 mg), which ranged from 9.5 kg to 12.9 kg [100]

Its not an either/or situation

This area of research explores GHs broader role in immune regulation and cellular defense

Recently, the weight-lowering effect of combined amylin/leptin agonism in human obesity was evaluated using the analogues pramlintide/metreleptin, respectively